가토의 대퇴부에 Calcium Metaphosphate로 코팅된 임플란트 매식후 골유착에 관한 비교 연구
Comparative Study on Osseointegration of Calcium Metaphosphate (CMP) Coated Implant to RBM Implant in the Femur of Rabbits
강영주, 김기현, 이재열, 이주민, 안상욱, 송진우, 정유진, 신상훈,
소속 상세정보
강영주 ( Kang Young-Joo ) - 부산대학교 치의학전문대학원 구강악안면외과학교실
김기현 ( Kim Ki-Hyun ) - 부산대학교 치의학전문대학원 구강악안면외과학교실
이재열 ( Lee Jae-Yeol ) - 부산대학교 치의학전문대학원 구강악안면외과학교실
이주민 ( Lee Ju-Min ) - 부산대학교 치의학전문대학원 구강악안면외과학교실
안상욱 ( Ahn Sang-Wook ) - 부산대학교 치의학전문대학원 구강악안면외과학교실
송진우 ( Song Jin-Woo ) - 부산대학교 치의학전문대학원 구강악안면외과학교실
정유진 ( Jung Eu-Gene ) - 부산대학교 치의학전문대학원 구강악안면외과학교실
신상훈 ( Shin Sang-Hun ) - 부산대학교 치의학전문대학원 구강악안면외과학교실
KMID : 0360120100320060511
Abstract
Purpose: This study was conducted in order to compare the efficacy of osseointegration of three different calcium metaphosphate(CMP) coated implants in the rabbit’s femur.
Materials and Methods: Twenty four rabbits and three different type of CMP coated implants and RBM implants were used in this study. The animals were divided into 4 groups on the basis of implant surface characteristics. Two implants were installed into the condyle of femur of each rabbits. The animals were sacrificed at 2 and 4 weeks after installation. The undecalcified specimens were prepared for histological, radiological examination and histomorphometric analysis of implant-bone contact ratios(BIC) and bone area ratio(BA).
Results: Two implants were failed to osseointegrate and implant success rate was 95.2%. There were not any significant inflammatory response in all groups. Fluorescent image at 4 weeks shows that remodeling is slower in RBM group than CMP group. CMPIII showed more active remodeling than CMPI, II. In histomorphologic analysis, BIC ratio at 2 weeks was lower than 4 weeks.
Conclusion: The results suggest that the ratios of CMP coated implants were higher than that of RBM control group but there is no significantly difference between RBM group and CMP group. In conclusion, CMP coated implant had more clinical availability than RBM implants.
키워드
Calcium metaphosphate; Coated implant
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